Scientists may need to rework on genes that control ageing: NIH

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New York, June 27 | Only 30 per cent of human genes, that are traditional hallmarks of ageing, may be directly involved in the process of ageing, finds a study led by an Indian-American researcher at the US National Institutes of Health (NIH).

The study suggests scientists may need to rethink which genes actually control ageing.

To understand, the researchers fed fruit flies with antibiotics and monitored the lifetime activity of hundreds of genes that scientists have traditionally thought control ageing.

To their surprise, the antibiotics not only extended the lives of the flies but also dramatically changed the activity of many of these genes. Their results suggested that only about 30 per cent of the genes traditionally associated with ageing set an animal’s internal clock while the rest reflect the body’s response to bacteria.

“For decades, scientists have been developing a hit list of common ageing genes. These genes are thought to control the aging process throughout the animal kingdom, from worms to mice to humans,” said Edward Giniger, from the NIH’s National Institute of Neurological Disorders and Stroke (NINDS).

“We were shocked to find that only about 30 per cent of these genes may be directly involved in the ageing process. We hope that these results will help medical researchers better understand the forces that underlie several age-related disorders,” he added. The findings are published in the journal iScience.

For the study, the team raised newborn male flies — of a type of fruit fly called Drosophila — on antibiotics to prevent bacteria growth. At first, they thought that the antibiotics would have little or no effect. But, when they looked at the results, they saw something interesting. The antibiotics lengthened the fly’s lives by about six days, from 57 days for control flies to 63 for the treated ones.

“This is a big jump in age for flies. In humans, it would be the equivalent of gaining about 20 years of life,” said lead author Arvind Kumar Shukla, post-doctoral researchers at the varsity.

“We were totally caught off guard and it made us wonder why these flies took so long to die,” Shukla added.

Shukla and his team looked for clues in the genes of the flies. They used advanced genetic techniques to monitor gene activity in the heads of 10, 30, and 45-day old flies.

“At first, we had a hard time believing the results. Many of these genes are classical hallmarks of ageing and yet our results suggested that their activity is more a function of the presence of bacteria rather than the ageing process,” said Shukla.

Source: IANS

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Does MBA really help in getting a better job offer ?

Does MBA really help in getting a better job offer ?

Most students pursuing an MBA come with the sole objective of having a decent job offer or a promotion in the existing job soon after completion of the MBA. And most of them take loans to pursue this career dream. According to a recent survey by education portal Campusutra.com  74% MBA 2022-24 aspirants said they would opt for education loans.

There are exceptional cases like those seeking master’s degree or may have a family business to take care of or an entrepreneurial venture in mind. But the exception cases are barely 1%. For the rest 99%, a management degree is a ticket to a dream job through campus placements or leap towards career enhancements. Stakes are high as many of them quit their jobs which essentially means loss of 2 years of income, apprehension and uncertainty of the job market. On top of that, the pressure to pay back the education loans. Hence the returns have to be high. There is more than just the management degree. Colleges need to ensure that they offer quality management education which enables them to be prepared for not just the demands of recruiters and for a decent job but also to sustain and achieve, all along their career path.

  • So, what exactly are the B Schools doing to prepare their students for the job market and make them industry ready ?
  •  Are B schools ready to deliver and prepare the future business leaders to cope up with the disrupted market ?  

These are the two key questions every MBA aspirant needs to ask, check and validate before filling the MBA application forms of management institutes. And worth mentioning that these application forms do not come cheap. An MBA aspirant who may have shortlisted 5 B Schools to apply for, may end up spending Rs 10,000.00 to Rs 15,000.00 just buying MBA / PGDM application forms.

While internship and placements data of some management institutes clearly indicates that recruiters today have specific demands. The skill sets looked for are job centric and industry oriented. MBA schools which have adopted new models of delivery and technology, redesigned their courses, built an effective evaluation process and prepared the students to cope with the dynamic business scenario, have done great with campus placements despite the economic slow down.

However, the skill set being looked for by a consulting company like Deloitte or KPMG may be quite different from FMCG or a manufacturing sector. Institutes need to acknowledge this fact and act accordingly.

  • Management institutes should ensure that students are intellectually engaged, self motivated and adapt to changes fast. In one word ‘VUCA ready’.
  • B Schools should encourage students to participate in national and international competitive events, simulations of business scenarios.
  • Institutes should have the right mix of faculty members with industry exposure and pure academics.

The placement records of 2021 across top management institutes indicated the fact that recruitment is happening, skilled talent is in demand and certain management institutions continued to attract recruiters even in the middle of an ongoing crisis.

It is time, all management institutes rise to the occasion, understand market realities and identify areas of improvement at both ends – students and faculty.

After all, the stakes are high at both ends. B Schools taking corrective measures will stay while those which are lagging will end up shutting down.

Author Name : Nirmalya Pal

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