Omicron’s latest subvariant BA.2.12.1 proves virus not declining: Report

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New York, May 2 | Omicron’s latest subvariant BA.2.12.1, responsible for about one-fourth of Covid-19 cases in the US, shows that the virus is not showing any signs of decline even over two years after it was first detected in humans.

BA.2.12.1 has also been detected in Australia and New Zealand.

Preliminary research suggests it is about 25 per cent more transmissible than the BA.2 subvariant that is currently dominant nationally, according to the Centers for Disease Control and Prevention.

According to virologists, although the SARS-CoV-2 virus has repeatedly changed its structure and chemistry, it still has abundant evolutionary space to explore, Washington Post reported.

While existing vaccination can still reduce the risk of severe Covid disease, the variants can evade many of the neutralising antibodies that are the immune system’s front line of defence.

“It’s evolving at a fairly rapid rate. I do think we need to aggressively consider whether we should update vaccines, and do it soon,” Jesse Bloom, a computational biologist at the Fred Hutchinson Cancer Research Center in Seattle was quoted as saying.

“The evolution is much more rapid and expansive than we initially estimated,” added Michael Osterholm, infectious-disease expert at the University of Minnesota.

“Every day I wake up, I fear there will be a new subvariant that we will have to consider. . . We’re seeing sub-variants of sub-variants,” he added.

Other mutations include BA.4 and BA.5, recently identified by scientists in South Africa. It has led to a fresh wave of Covid in the country.

Besides South Africa, the sub variants have also been detected in more than 20 countries including Australia, Austria, Belgium, China, Israel, Denmark, France, Germany, Pakistan, UK, US and Switzerland.

Apart from mutation, the virus has another trick up its sleeve: recombination. It happens when two distinct strains infect a single host simultaneously and their genes become entangled, the Post reported.

The recombination process is the origin of what’s known as Omicron XE. That recombinant probably emerged from a person co-infected with the original Omicron variant and the BA.2 subvariant.

It was always possible in theory, but the identification of actual recombinants provides “proof of concept,” Jeremy Luban, a virologist at the University of Massachusetts Medical School was quoted as saying.

The worst-case scenario would be the emergence of a variant or recombinant that renders current vaccines largely ineffective at blocking severe disease. But so far, that hasn’t happened. And no “recombinant” has spread like Omicron or other recent variants and sub-variants, the report said.

Source: IANS

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Weekly Technical Share Market Outlook

Weekly Technical Share Market Outlook

The Indian market recovered sharply on the last trading day amid the weekend after a continuous fall. Market has managed to halt above 16000 Nifty levels after continuous losing streak. Index reacted violently, grasping Indian as well as global factors throughout the week. Simultaneously, Inflation is catching up and profit margins are taking a hit.

 

Sensex advanced 1532 points or 2.90 percent while Nifty gained 484 points or 3.07 percent in a week. Simultaneously, Bank nifty has overcome bear’s dominance ending the session with 3.49 percent gain. Sectorally,Nifty Metal saw the highest gains of 7.40 percent followed by the Realty and Auto added over 4% gain. On the flip side Nifty IT tumbled 2.82 percent on weekly basis. Midcap and Small Cap measures rising nearly 2 percent as well.

In Nifty stock, EICHERMOT gained 11.31% while TECHM lost 5.98% on a weekly basis. INDIA VIX closes at 23.10 suggests volatility driven market is going to remain intact. Coming to the OI Data, on the call side highest OI witnessed at 17000 Nifty followed by 16800 Nifty strike price while on the put side, the highest OI was at 16000 Nifty followed by 15800 Nifty strike price. Technically, Nifty has formed a Tweezer Bottom type pattern in the weekly chart suggesting a short term buying rally may drive the market until monthly expiry. On the daily chart, price has rebounded from the lower Bollinger band as well.

Momentum indicators MACD & Stochastic were trading with a positive crossover & reversed from oversold zone. However, Index is still struggling to get the support of 50 Simple Moving Average in daily chart. Short term investors and traders are advised to work with option strategies to neutralize the volatility. Overall, Nifty is having support at 15700 mark while on the upside 16700 followed by 16500 may act as an immediate resistance. While Bank nifty has support around 32500 while resistance is placed at 36000 on weekly chart.

Sumeet Bagadia
Executive Director
Choice Broking

Source: Choice India

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